100 Demons, by Lynda Barry.
Barry's comeeks have always flirted with autobiography. In her Salon series (currently on hiatus, goddamn it), she finally plunges in with both feet, undertaking stories of her own frustrations, humiliations, and satisfactions growing up. Powerful, real emotion radiates from every panel. Her drawings of herself and her stand-ins have always radiated self-loathing, and I find myself strangely comforted by the fact that she draws her current self as a moderately attractive woman.